About this blog

CRIT is no longer adding posts or updating the CRITical Thinking blog.

CRITical Thinking is a blog written by staff, directors, and friends of the Collaboration for Research Integrity and Transparency (CRIT), a joint program of Yale Law School, Yale School of Public Health, and Yale School of Medicine. CRIT's mission is to promote health by improving the integrity and transparency of biomedical and clinical research.

This blog is published by and reflects the personal views of the individual authors, in their individual capacities. It does not purport to represent Yale University's institutional views, if any. No representation is made about the accuracy of the information, which solely constitutes the authors’ personal views on issues discussed. The information contained in this blog is provided only as general information and personal opinions, and blog topics may be updated after being initially posted.


CRITical Thinking Blog

Postmarketing requirements: Additional transparency may be necessary to strengthen FDA’s lifecycle evaluation process

May 24, 2018
By Joshua D. Wallach, Joseph S. Ross

In the United States, the Food and Drug Administration (FDA) faces a challenging task—striking a balance between allowing promising new drugs to enter the market as quickly as possible and ensuring that they are safe and effective.

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Evaluating the evidence used by the US Food and Drug Administration during the drug approval process

May 18, 2018
By Joshua D. Wallach, Joseph S. Ross

Over the past few years, the US Food and Drug Administration (FDA) has faced continual pressure to accelerate the review and approval of new drugs, in order to promote innovation and provide rapid access to new treatments for patients with serious life-threatening conditions.

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CRIT releases French, Spanish, and Portuguese Translations of “What’s in Your Medicine Cabinet?”

March 22, 2018
By Margaret McCarthy

The Yale Collaboration for Research Integrity and Transparency has just released French, Spanish, and Portuguese versions of

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Work Locally, Coordinate Globally

February 22, 2018
By Joel Lexchin

I think that there are a number of problems that are common in all parts of the world. Among these are: the political and economic power of the pharmaceutical industry, the way that intellectual property rights interfere with access and affordability of medicines, the poor evidentiary base for the safety and effectiveness of many medicines and the increasing ties between regulators and industry, that result in the weakening of regulatory standards.

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